Article
A comprehensive atlas of full-length Arabidopsis eccDNA populations identifies their genomic origins and epigenetic regulation.
PLoS biology - 1 Jul 2025
Zaidi Syed Shan-E-Ali, Shakir Sara, De Kort Hanne, Mehta Devang, Nguyen Vu, Gutzat Ruben, Vanderschuren Hervé
Abstract excerpt
Extrachromosomal circular DNA (eccDNA) has been described in several eukaryotic species and has been shown to impact phenomena as diverse as cancer and herbicide tolerance. EccDNA is thought to arise mainly through transposable element (TE) mobilization. Because studies based on short-read sequencing cannot efficiently identify full-length eccDNA forms generated from TEs, we employed the CIDER-Seq pipeline based...
Read the complete abstract on PubMedTopics
- Arabidopsis
- Epigenesis, Genetic
- DNA Transposable Elements
- DNA Methylation
- Genome, Plant
- DNA, Plant
