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Article

Th2 mRNA gene expression analysis separates Prurigo nodularis into two immune signature groups

2 Jul 2025

Abstract excerpt

BACKGROUND AND OBJECTIVES: Prurigo nodularis (PN) is a severe, intensely pruritic subtype of chronic prurigo for which the molecular basis and interplay between pathophysiologic mechanisms and clinical manifestations are poorly understood. METHODS: LOTUS-PN was a longitudinal observational study that included 54 participants from 11 centers and was designed to improve disease understanding. Protein expression,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40600744
DOI: 10.1111/jdv.20812

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