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Article

Sequencing of a Dairy Isolate Unlocks Kluyveromyces marxianus as a Host for Lactose Valorization.

ACS synthetic biology - 18 Jul 2025

Thornbury Mackenzie, Knoops Adrien, Summerby-Murray Iain, Dhaliwal James, Johnson Sydney, Utomo Joseph Christian, Joshi Jaya, Narcross Lauren, Remondetto Gabriel, Pouliot Michel, Whiteway Malcolm, Martin Vincent J J

Abstract excerpt

The use of genetically modified nonconventional yeast provides significant potential for the bioeconomy by diversifying the tools available for the development of sustainable and novel products. In this study, we sequenced and annotated the genome of Kluyveromyces marxianus Y-1190 to establish it as a platform for lactose valorization. The strain was chosen for rapid growth on lactose-rich dairy permeate, high...

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PMID: 40629255
DOI: 10.1021/acssynbio.5c00096

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