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GenomeFISH: genome-based fluorescence in situ hybridization for strain-level visualization of microbial communities

1 Jan 2025

Abstract excerpt

Fluorescence in situ hybridization (FISH) is a powerful tool for visualizing the spatial organization of microbial communities. However, traditional FISH has several limitations, including limited phylogenetic resolution, difficulty visualizing certain lineages, and the design and optimization of new probes is time consuming and does not scale to the known diversity of microbial life. Here, we present GenomeFISH,...

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PMID: 40621946
DOI: 10.1093/ismejo/wraf138

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