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Article

Juvenile idiopathic arthritis and primary ovarian failure: a two-sample Mendelian randomization analysis in a mixed-gender cohort.

Frontiers in endocrinology - 1 Jan 2024

Mo Yuanhang, Shang Anquan, Wei Guoguo, Xu Donghui, Hou Yuxi, Shao Xiaowen, Yue Chaoyan

Abstract excerpt

Background: The causal relationship between juvenile idiopathic arthritis (JIA) and primary ovarian failure (POF) remains uncertain. To elucidate this relationship, we employed a two-sample Mendelian randomization analysis. Methods: The single nucleotide polymorphisms (SNPs) associated with JIA were obtained from a previously published genome-wide association study (GWAS), while the pooled data for POF originated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38818501
DOI: 10.3389/fendo.2024.1340993
PMCID: PMC11137172

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