Article
SMAD7, an antagonist of TGF-beta signaling, is a candidate of prenatal skeletal muscle development and weaning weight in pigs.
Molecular biology reports - 1 Apr 2016
Hua Chaoju, Wang Zishuai, Zhang Jianbing, Peng Xing, Hou Xinhua, Yang Yalan, Li Kui, Tang Zhonglin
Abstract excerpt
SMAD7 promotes and enhances skeletal muscle differentiation by inhibiting transforming growth factor beta (TGF-β)/activin signaling and bone morphogenetic protein (BMP) pathways. However, its function, the mechanism regulating its translation, and its association with production meat traits remain unclear in pigs. In this study, we explored SMAD7 gene spatio-temporal and tissue distribution, conducted a single...
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