Article
Single nucleotide polymorphism scanning and expression of the FRZB gene in pig populations.
Gene - 15 Jun 2014
Wang Zhixiu, Li Qinggang, Zhang Bo, Lu Yunfeng, Yang Yuzeng, Ban Dongmei, Zhang Hao
Abstract excerpt
Secreted frizzled-related protein 3 (sFRP3), encoded by the gene FRZB, is a member of the sFRP family with important roles in inhibition of the Wnt signalling pathway through competitive binding of the Wnt receptor. Here, we investigated pig FRZB as a candidate gene for growth traits and identified three polymorphic sites, an insertion (A-532B) and two SNPs (G636A and C650T) in its 5'-UTR. The genotype...
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