Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Baseline vitamin D status, genetic susceptibility, and the risk of incident hepatocellular carcinoma.

International journal of cancer - 1 Nov 2025

Yu Chengxiao, Lin Fei, Tian Chan, Guo Haiyan, Lu Jing, Guo Wen, Duan Qingning, Jiang Longfeng, Zhang Qun, Song Ci

Abstract excerpt

High vitamin D concentrations may reduce the incidence of hepatocellular carcinoma (HCC), though results have been inconsistent. This study aimed to evaluate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and HCC, and to assess whether the genetic risk of HCC modifies this association. The prospective cohort study involved 447,028 individuals free of liver diseases in the UK Biobank. Serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Incidence

Share to Liver Neoplasms

Share to Proportional Hazards Models

Share to United Kingdom

Share to Vitamin D

Source

Identifiers

PMID: 40611365
DOI: 10.1002/ijc.70003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Baseline vitamin D status, genetic susceptibility, and the risk of incident hepatocellular carcinoma.PMID 40611365Read ↗

Genome-wide meta-analysis identifies nine loci associated with higher risk of hepatocellular carcinoma developmentSemantic proximity Read ↗

Serum 25-hydroxyvitamin D, vitamin D-related variants, and risk of chronic liver disease.Semantic proximity Read ↗

Vitamin D receptor gene polymorphisms, bioavailable 25-hydroxyvitamin D, and hepatocellular carcinoma survival.Semantic proximity Read ↗

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development.Semantic proximity Read ↗

Genetic Susceptibility to Hepatocellular Carcinoma in Patients with Chronic Hepatitis Virus Infection.Semantic proximity Read ↗

Low vitamin D exposure and risk of nasopharyngeal carcinoma: Observational and genetic evidence from a multicenter case-control study.Semantic proximity Read ↗

Epidemiological characteristics and risk factors of hepatocellular carcinomaSemantic proximity Read ↗

Significance of Vitamin D Receptor Gene Polymorphisms for Risk of Hepatocellular Carcinoma in Chronic Hepatitis CSemantic proximity Read ↗

Relationship among serum 25-hydroxyvitamin D, fibrosis stage, genetic susceptibility, and risk of severe liver disease.Semantic proximity Read ↗

Association of vitamin D receptor gene polymorphisms ApaI (rs7975232) and BsmI (rs1544410) with hepatocellular carcinoma susceptibility in Egyptian patients.Semantic proximity Read ↗

Vitamin D status and cancer incidence and mortality.Semantic proximity Read ↗

Genetic insights into hepatocellular carcinoma: the role of VDR FokI (rs2228570) and TaqI (rs731236) polymorphisms in Egyptian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.