Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses.

Nature communications - 1 Jul 2025

Shen Jie, Valentim Wander, Friligkou Eleni, Overstreet Cassie, Choi Karmel W, Koller Dora, O'Donnell Christopher J, Stein Murray B, Gelernter Joel, Lv Haitao, Sun Ling, Falcone Guido J, Polimanti Renato, Pathak Gita A

Abstract excerpt

Patients with post-traumatic stress disorder face increased cardiovascular risk. This study examines shared genetic regions between post-traumatic stress disorder and 246 cardiovascular conditions across electronic health records, 82 cardiac imaging, and health behaviors defined by Life's Essential 8. Post-traumatic stress disorder is genetically correlated with cardiovascular diagnoses in 33 regions, imaging...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiovascular Diseases

Share to Cardiovascular Health and Risk Factors

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Stress Disorders, Post-Traumatic

Source

Open in PubMed Open full text

Identifiers

PMID: 40595462
DOI: 10.1038/s41467-025-60487-w
PMCID: PMC12217169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses.PMID 40595462Read ↗

Genetics of posttraumatic stress disorder and cardiovascular conditions using Life’s Essential 8, Electronic Health Records, and Heart ImagingSemantic proximity Read ↗

Leveraging large-scale genetics of PTSD and cardiovascular disease demonstrates robust shared risk and improves risk prediction accuracySemantic proximity Read ↗

Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health recordsSemantic proximity Read ↗

Leveraging Large-Scale Genetics of PTSD and Cardiovascular Disease to Demonstrate Robust Shared Risk and Improve Risk Prediction Accuracy.Semantic proximity Read ↗

Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health records.Semantic proximity Read ↗

Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits.Semantic proximity Read ↗

A genetic exploration of the relationship between Posttraumatic Stress Disorder and cardiovascular diseasesSemantic proximity Read ↗

A genetic exploration of the relationship between posttraumatic stress disorder and cardiovascular diseases.Semantic proximity Read ↗

Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory OutcomesSemantic proximity Read ↗

Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program.Semantic proximity Read ↗

Common genetic variation impacts stress response in the brainSemantic proximity Read ↗

Shared Genetic Factors Between Stress-related Disorders and Cardiovascular DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.