Article
Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health records.
Molecular psychiatry - 1 Oct 2022
Polimanti Renato, Wendt Frank R, Pathak Gita A, Tylee Daniel S, Tcheandjieu Catherine, Hilliard Austin T, Levey Daniel F, Adhikari Keyrun, Gaziano J Michael, O'Donnell Christopher J, Assimes Themistocles L, Stein Murray B, Gelernter Joel
Abstract excerpt
The association between coronary artery disease (CAD) and posttraumatic stress disorder (PTSD) contributes to the high morbidity and mortality observed for these conditions. To understand the dynamics underlying PTSD-CAD comorbidity, we investigated large-scale genome-wide association (GWA) statistics from the Million Veteran Program (MVP), the UK Biobank (UKB), the Psychiatric Genomics Consortium, and the...
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