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Article

A genetic exploration of the relationship between posttraumatic stress disorder and cardiovascular diseases.

Translational psychiatry - 4 Jan 2025

Lukas Eva, Veeneman Rada R, Smit Dirk J A, Ahluwalia Tarunveer S, Vermeulen Jentien M, Pathak Gita A, Polimanti Renato, Verweij Karin J H, Treur Jorien L

Abstract excerpt

Experiencing a traumatic event may lead to Posttraumatic Stress Disorder (PTSD), including symptoms such as flashbacks and hyperarousal. Individuals suffering from PTSD are at increased risk of cardiovascular disease (CVD), but it is unclear why. This study assesses shared genetic liability and potential causal pathways between PTSD and CVD. We leveraged summary-level data of genome-wide association studies...

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Identifiers

PMID: 39755697
DOI: 10.1038/s41398-024-03197-z
PMCID: PMC11700205

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