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Article

Leveraging Large-Scale Genetics of PTSD and Cardiovascular Disease to Demonstrate Robust Shared Risk and Improve Risk Prediction Accuracy.

The American journal of psychiatry - 1 Nov 2022

Seligowski Antonia V, Misganaw Burook, Duffy Lucie A, Ressler Kerry J, Guffanti Guia

Abstract excerpt

OBJECTIVE: Individuals with posttraumatic stress disorder (PTSD) are significantly more likely to be diagnosed with cardiovascular disease (CVD) (e.g., myocardial infarction, stroke). The evidence for this link is so compelling that the National Institutes of Health convened a working group to determine gaps in the literature, including the need for large-scale genomic studies to identify shared genetic risk. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36069022
DOI: 10.1176/appi.ajp.21111113
PMCID: PMC9633348

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