Article
Meiotic nondisjunction and translocation segregation in dwarf (dw/dw) and control T(1;13)70H heterozygous mice.
The Journal of heredity - 1 Jan 2000
Wauben-Penris P J, van der Hoeven F A
Abstract excerpt
The meiotic behavior of translocation heterozygous T70 (1;13)H/+ male mice with a Snell dwarf (dw/dw) genotype was compared with that of nondwarf T70H/+ controls. A four-fold increase in the nondisjunction frequency of the normal bivalents occurred as a consequence of the dwarf genotype. This inc...
Topics
- Animals
- Body Weight
- Dwarfism
- Female
- Genotype
- Heterozygote
- Male
- Meiosis
- Mice
- Mice, Mutant Strains
- Nondisjunction, Genetic
- Oocytes
- Organ Size
- Species Specificity
- Sperm Count
- Spermatocytes
- Testis
- Translocation, Genetic
