Article
A study of meiotic pairing, nondisjunction and germ cell death in laboratory mice carrying Robertsonian translocations.
Genetical research - 1 Jun 1996
Everett C A, Searle J B, Wallace B M
Abstract excerpt
Frequencies of anaphase I nondisjunction, germ cell death and pairing abnormalities at pachytene were assessed in male mice singly heterozygous and homozygous for the Robertsonian (Rb) translocations: Rb (1.3)1Bnr, Rb(11.13)4Bnr and Rb(10.11)8Bnr. Rb homozygotes showed low frequencies of nondisjunction but substantial germ cell death. This germ cell death could not be attributed to problems at pachytene as Rb...
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