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Update of the sideroflexin (SLC56) gene family

20 Jun 2025

Abstract excerpt

The human sideroflexin (SFXN) gene family, also classified as solute carrier family 56 (SLC56), encodes a group of five mitochondrial transmembrane proteins (SFXN1-SFXN5) involved in key aspects of mitochondrial metabolism, cellular homeostasis, and development. SFXNs are highly conserved across eukaryotic species, with evolutionary the origin traced back to the earliest metazoans. Functionally, each of the five...

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PMID: 40542427
DOI: 10.1186/s40246-025-00779-w

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