Article
Identification of a transposon variant of Porphyromonas gingivalis expressing long Mfa1 fimbriae due to mfa2 inactivation.
Journal of oral biosciences - 1 Sept 2025
Miwa Naoyoshi, Fujimoto Miyuna, Sakae Kotaro, Iwase Tomohiko, Hirohata Makoto, Naiki Yoshikazu, Nishikawa Kiyoshi, Nawa Hiroyuki, Hasegawa Yoshiaki
Abstract excerpt
OBJECTIVES: Fimbriae expressed by Porphyromonas gingivalis, a periodontal pathogen, play a pivotal role in biofilm formation. In the type strain ATCC 33277, Mfa1 fimbriae form short structures anchored to the cell surface by Mfa2, an outer membrane protein involved in regulation of fimbrial length. Mfa1, the major fimbrilin, is classified into three genotypic types-mfa170A, mfa170B, and mfa153-based on gene...
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