Article
Isolation and characterization of transposon-induced mutants of Porphyromonas gingivalis deficient in fimbriation.
Microbial pathogenesis - 1 Jan 1998
Watanabe-Kato T, Hayashi J I, Terazawa Y, Hoover C I, Nakayama K, Hibi E, Kawakami N, Ikeda T, Nakamura H, Noguchi T, Yoshimura F
Abstract excerpt
Fimbriae are considered to be an important virulence factor of Porphyromonas gingivalis. In order to identify genes essential for fimbriation, other than fimA which encodes the major subunit protein of fimbriae, transposon mutagenesis and immunological screening techniques were used to isolate fimbria-deficient mutants. R751::*Omega4, a suicide vector that carries Tn4351, was transferred from Escherichia coli to...
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