Article
Diversity analysis of genes encoding Mfa1 fimbrial components in Porphyromonas gingivalis strains.
PloS one - 1 Jan 2021
Sakae Kotaro, Nagano Keiji, Furuhashi Miyuna, Hasegawa Yoshiaki
Abstract excerpt
Porphyromonas gingivalis, a gram-negative anaerobic bacterium, is associated with the development of periodontal disease. The genetic diversity in virulence factors, such as adhesive fimbriae, among its strains affects the bacterial pathogenicity. P. gingivalis generally expresses two distinct types of fimbriae, FimA and Mfa1. Although the genetic diversity of fimA, encoding the major FimA fimbrilin protein, has...
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