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No two are alike: on the role of Klebsiella pneumoniae permeability barriers in antibiotic susceptibility and persistence

17 Jun 2025

Abstract excerpt

ABSTRACT Klebsiella pneumoniae and Escherichia coli cause a broad range of human infections with multidrug-resistant strains presenting serious therapeutic challenges in clinics. The discovery of new antibiotics effective against these pathogens is hindered because of effective drug permeability barriers comprising active efflux pumps acting synergistically with the low-permeability outer membrane. In this study,...

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Share to Antibiotic Resistance in Bacteria
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PMID: 40525411
DOI: 10.1128/aac.00085-25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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