Article

Strain-dependent contribution of the AcrAB-TolC efflux pump to <i>Klebsiella pneumoniae</i> physiology

2025-09-26

Abstract excerpt

Klebsiella pneumoniae is a prominent opportunistic pathogen increasingly associated with multidrug resistance and virulence. One of the main mechanisms of antimicrobial resistance in K. pneumoniae is active efflux, primarily mediated by the Resistance-Nodulation-Division (RND) family of pumps. AcrAB-TolC is the key RND efflux pump in K. pneumoniae , regulated by the transcriptional activator RamA and its repress...

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Literature Corpus work: 1860f222-4e55-5f32-a45e-ba2019aa5245
DOI: 10.1101/2025.09.26.678718

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