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Article

Permeability barriers of Gram‐negative pathogens

4 Jun 2019

Abstract excerpt

Most clinical antibiotics do not have efficacy against Gram-negative pathogens, mainly because these cells are protected by the permeability barrier comprising the two membranes with active efflux. The emergence of multidrug-resistant Gram-negative strains threatens the utility even of last resort therapeutic treatments. Significant efforts at different levels of resolution are currently focused on finding a...

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PMID: 31165502
DOI: 10.1111/nyas.14134

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