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Article

The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria.

Nature reviews. Microbiology - 1 Dec 2008

Pagès Jean-Marie, James Chloë E, Winterhalter Mathias

Abstract excerpt

Gram-negative bacteria are responsible for a large proportion of antibiotic-resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm. The outer membrane contains various protein channels, called porins, which are involved in the influx of various compounds, including several classes of antibiotics. Bacterial...

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Identifiers

PMID: 18997824
DOI: 10.1038/nrmicro1994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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