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Article

Fatty acid binding proteins 5 and 7 differentially modulate phenotypic response to acute Δ9-tetrahydrocannabinol in female mice.

Physiology & behavior - 1 Oct 2025

Penman Samantha L, Marion Matthew, Hamilton John, Clouse Grace, Roeder Nicole M, Owada Yuji, Kagawa Yoshiteru, Thanos Panayotis K

Abstract excerpt

Fatty acid binding proteins (FABPs) are important regulatory proteins within the endocannabinoid system (ECS) which have also been implicated as carriers of Δ9-tetrahydrocannabinol (THC). The goal of this study was to further characterize how FABPs 5 and 7 interact with THC in vivo using transgenic knockout mice. Mice with or without FABP5 or FABP7 were administered a single 15 mg/kg dose of intraperitoneal...

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Identifiers

PMID: 40517922
DOI: 10.1016/j.physbeh.2025.114999

Genes

FABP5
FABP7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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