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Article

Functional consequences of genetic variations in DgoR, a GntR/FadR family transcriptional repressor of D-galactonate metabolism in Escherichia coli.

Journal of bacteriology - 24 Jul 2025

Singh Swati, Mishra Rajesh, Kakkar Richa Ashok, Singla Shivam, Pratap Akhil, Sharma Gaurav, Sharma Monika, Chaba Rachna

Abstract excerpt

Genetic variations in transcriptional regulators (TRs) of metabolic loci can influence host-bacterial interactions by affecting carbon utilization. Although the metabolism of sugar acids, including D-galactonate, is extensively implicated in the colonization and virulence of enteric bacteria, there has been no investigation on the extent of variations in their pathway-specific TRs. DgoR, the TR of D-galactonate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40497739
DOI: 10.1128/jb.00103-25
PMCID: PMC12288454

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