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Article

TetR and OmpR family regulators in natural product biosynthesis and resistance

24 Oct 2023

Abstract excerpt

This article provides a comprehensive review and sequence-structure analysis of transcription regulator (TR) families, TetR and OmpR/PhoB, involved in specialized secondary metabolite (SSM) biosynthesis and resistance. Transcription regulation is a fundamental process, playing a crucial role in orchestrating gene expression to confer a survival advantage in response to frequent environmental stress conditions....

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PMID: 37874037
DOI: 10.1002/prot.26621

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