Article
Association of interferon gamma gene polymorphisms with BK virus infection among Hispanic renal allograft recipients.
Transplantation - 27 Mar 2014
Vu Don, Sakharkar Prashant, Shah Tariq, Naraghi Robert, Yasir Qazi, Hutchinson Ian, Min David
Abstract excerpt
BACKGROUND: BK virus nephropathy is one of the most common viral infections that affect up to 10% of renal transplant recipients (RTRs), causing allograft dysfunction and graft loss. Interferon-gamma (IFN-γ) gene polymorphisms have been associated with parvovirus B19, hepatitis C virus, HIV-1/AIDS infection, cytomegalovirus viremia, and disease. IFN-γ is known to have potent inhibitory effects on BK virus gene...
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