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Circadian Gene BMAL1 Regulation of Cellular Senescence in Thyroid Aging

28 May 2025

Abstract excerpt

As global aging accelerates, the incidence of thyroid diseases, particularly hypothyroidism, is rising in the elderly. The thyroid-stimulating hormone (TSH) levels increase in healthy elderly populations. However, whether the thyroid undergoes cellular senescence and how this relates to thyroid hormone (TH) synthesis remain unclear. To investigate the molecular and functional characteristics of thyroid aging, we...

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PMID: 40434135
DOI: 10.1111/acel.70119

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