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Article

Transcriptome Network Analysis Reveals Aging-Related Mitochondrial and Proteasomal Dysfunction and Immune Activation in Human Thyroid

29 Mar 2018

Abstract excerpt

BACKGROUND: Elucidating aging-related transcriptomic changes in human organs is necessary to understand the aging physiology and mechanisms, but little is known regarding the thyroid gland. We investigated aging-related transcriptomic alterations in the human thyroid gland and characterized the related molecular functions. METHODS: Publicly available RNA sequencing data of 322 thyroid tissue samples from the...

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PMID: 29652618
DOI: 10.1089/thy.2017.0359

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