Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Model of Non-Homologous Recombination Mediated by HIV-1 Reverse Transcriptase Explaining Sequence Motif Duplications That Confer a Replication Fitness Advantage

7 May 2025

Abstract excerpt

The Reverse Transcriptase of the Human Immunodeficiency Virus (HIV) is distinguished by its high rate of homologous recombination. A less-studied consequence of this phenomenon is the increased occurrence of non-homologous recombination, which results in length polymorphism. While most of these genome-wide variations are sporadic, some provide a replication advantage to variant strains, such as those in the Long...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40431692
DOI: 10.3390/v17050680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Model of Non-Homologous Recombination Mediated by HIV-1 Reverse Transcriptase Explaining Sequence Motif Duplications That Confer a Replication Fitness AdvantagePMID 40431692Read ↗

A Model of Non-Homologous Recombination Mediated by HIV-1 Reverse Transcriptase Explaining Sequence Motif Duplications That Confer a Replication Fitness AdvantageSemantic proximity Read ↗

In vivo characteristics of human immunodeficiency virus type 1 intersubtype recombination: determination of hot spots and correlation with sequence similaritySemantic proximity Read ↗

Identifying recombination hot spots in the HIV-1 genome.Semantic proximity Read ↗

The Remarkable Frequency of Human Immunodeficiency Virus Type 1 Genetic RecombinationSemantic proximity Read ↗

The origin of genetic diversity in HIV-1.Semantic proximity Read ↗

Mechanisms and factors that influence high frequency retroviral recombination.Semantic proximity Read ↗

Recombination in viruses: mechanisms, methods of study, and evolutionary consequences.Semantic proximity Read ↗

Molecular Mechanisms of Recombination Restriction in the Envelope Gene of the Human Immunodeficiency VirusSemantic proximity Read ↗

Genetic recombination and its role in the development of the HIV-1 pandemicSemantic proximity Read ↗

Recurrent recombination and insertion–deletion events shape the genome-wide evolutionary history of the Coronaviridae familySemantic proximity Read ↗

Re-analysis of 34 full-length HIV-1 intersubtype recombinant sequences.Semantic proximity Read ↗

HIV-1 recombination: an experimental assay and a phylogenetic approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.