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Single-cell transcriptome analysis profiles cellular and molecular alterations in aortic tissue from patients with Behçet's syndrome.

Rheumatology (Oxford, England) - 1 Sept 2025

Wang Cong, Li Taotao, Zhu Junmin, Qiao Bokang, Qiao Zhiyu, Hu Haiou, Zhang Nan, Yu Hai, Zhao Honglei, Zhong Yongliang, Pan Lili, Gao Na

Abstract excerpt

OBJECTIVES: This study aims to analyse the expression profiles, phenotypes, functions and cell-cell communication of various cell subpopulations in the affected aortic tissues of patients with Behçet's syndrome (BS) at the transcriptomic level. METHODS: This study recruited six participants (three with BS and three with atherosclerosis) from Beijing Anzhen Hospital between January 2023 and June 2024, collected...

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PMID: 40372706
DOI: 10.1093/rheumatology/keaf252

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