Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Human Leukocyte Antigen (HLA) DRB1*13:02 Allele Protects against Dementia in Continental Western Europe

1 Nov 2019

Abstract excerpt

= 0.452, P = 0.008), even when adjusted for the prevalence of apolipoprotein E4 allele, a known risk factor for Alzheimer's disease. This finding documents the protective effect of DRB1*13:02 on dementia prevalence in CWE. Since the function of HLA class II genes is to aid in the elimination of pathogens by enabling the production of antibodies against their antigens in specific immunity, the protective effect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Immune responses and vaccinations
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40371383
DOI: 10.29245/2572.942x/2019/5.1253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Human Leukocyte Antigen (HLA) DRB1*13:02 Allele Protects against Dementia in Continental Western EuropePMID 40371383Read ↗

The HLA-DRB1*09:01-DQB1*03:03 haplotype is associated with the risk for late-onset Alzheimer’s disease in APOE $${{\varepsilon }}$$4–negative Japanese adultsSemantic proximity Read ↗

Shared Human Leukocyte Antigen (HLA) Coverage in dementia and Parkinson’s diseaseSemantic proximity Read ↗

Risk for Alzheimer's disease in older late-onset cases is associated with HLA-DRB1*03.Semantic proximity Read ↗

Cognitively healthy centenarians are characterized by lower frequencies of six disease-associated<i>HLA</i>allelesSemantic proximity Read ↗

Protective Effect of Human Leukocyte Antigen (HLA) Allele DRB1*13:02 on Age-Related Brain Gray Matter Volume Reduction in Healthy Women.Semantic proximity Read ↗

Immunogenetic Epidemiology of Dementia and Parkinson’s Disease in 14 Continental European Countries: Shared Human Leukocyte Antigen (HLA) ProfilesSemantic proximity Read ↗

HLA-C*07:01 and HLA-DQB1*02:01 protect against white matter hyperintensities and deterioration of cognitive function: A population-based cohort study.Semantic proximity Read ↗

Evolutionary Selection of APOEɛ4 Encourages Increased Focus on Immunity in Alzheimer's Disease.Semantic proximity Read ↗

HLA-A23/HLA-A24 serotypes and dementia interaction in the elderly: Association with increased soluble HLA class I molecules in plasma.Semantic proximity Read ↗

Human Leukocyte Antigen and microRNAs as Key Orchestrators of Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review.Semantic proximity Read ↗

Genetic factors related to the immune system in subjects at risk of developing Alzheimer's disease.Semantic proximity Read ↗

Association of the HLA-DQB1*02 allele with lower tauopathy in Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.