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Article

Causal relationships between depression, anxiety, and myopia: a two-sample Mendelian randomization study.

Eye (London, England) - 1 Aug 2025

Xu Shengsong, Wang Xiao, Xu Jinyi, Tang Xianghua, Hao Wenlong, Xiang Chuqi, Lei Xingyu, Wang Mengyi, Yang Xiao

Abstract excerpt

OBJECTIVES: To investigate the causal relationship between depression, anxiety, and myopia. METHODS: The multivariable Mendelian randomization (MR) design using summary statistics from independent genome-wide association studies (GWAS) was employed. The anxiety and depression, were used as exposures, and myopia was used as the outcome. Genetic variants associated with depression were derived using GWAS summary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40360801
DOI: 10.1038/s41433-025-03841-y
PMCID: PMC12274470

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