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Article

Primary and secondary gliosarcomas: clinical, molecular and survival characteristics.

Journal of neuro-oncology - 1 Nov 2015

Cachia David, Kamiya-Matsuoka Carlos, Mandel Jacob J, Olar Adriana, Cykowski Matthew D, Armstrong Terri S, Fuller Gregory N, Gilbert Mark R, De Groot John F

Abstract excerpt

Gliosarcoma is classified by the World Health Organization as a variant of glioblastoma. These tumors exhibit biphasic histologic and immunophenotypic features, reflecting both glial and mesenchymal differentiation. Gliosarcomas can be further classified into primary (de novo) tumors, and secondary gliosarcomas, which are diagnosed at recurrence after a diagnosis of glioblastoma. Using a retrospective review,...

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Identifiers

PMID: 26354773
DOI: 10.1007/s11060-015-1930-y
PMCID: PMC8323586

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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