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Article

MG53 deficiency mediated skeletal muscle dysfunction in chronic obstructive pulmonary disease via impairing mitochondrial fission

3 May 2025

Abstract excerpt

Myokine dysregulation and mitochondrial dysfunction are implicated in the pathogenesis of sarcopenia in chronic obstructive pulmonary disease. The objective of this study is to explore the role of myokines and mitochondrial dysfunction in sarcopenia in chronic obstructive pulmonary disease. We identified mitsugumin 53 and its clinical correlation through an enzyme-linked immunosorbent assay using the plasma...

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PMID: 40345073
DOI: 10.1016/j.redox.2025.103663

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