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Cardiac effects and clinical applications of MG53

28 Jun 2021

Abstract excerpt

Heart disease remains the leading cause of mortality globally, so further investigation is required to identify its underlying mechanisms and potential targets for treatment and prevention. Mitsugumin 53 (MG53), also known as TRIM72, is a TRIM family protein that was found to be involved in cell membrane repair and primarily found in striated muscle. Its role in skeletal muscle regeneration and myogenesis has...

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PMID: 34183055
DOI: 10.1186/s13578-021-00629-x

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