Article
High-Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients.
Cancer reports (Hoboken, N.J.) - 1 May 2025
Bold Nomin, Buyanbat Khurelsukh, Enkhtuya Ariya, Myagmar Nomin, Batbayar Gerelsuren, Sandag Zolzaya, Damdinbazar Dolgion, Oyunbat Nomuun, Boldbaatar Tuul, Enkhbaatar Ankhbayar, Baatarjav Gan-Erdene, Nanzaddorj Taivan, Oyunsuren Tsendsuren, Davaakhuu Gantulga
Abstract excerpt
BACKGROUND: Mongolia has the highest incidence of liver cancer worldwide, largely driven by a high prevalence of hepatitis virus infections. Mutations in oncogenes and tumor suppressor genes provide valuable insights into the molecular mechanisms of hepatocellular carcinoma (HCC). AIMS: This study aimed to investigate the prevalence of mutations in key oncogenes and tumor suppressor genes in Mongolian HCC...
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