Article

Assessments of TP53 and CTNNB1 gene hotspot mutations in circulating tumour DNA of hepatitis B virus-induced hepatocellular carcinoma

2023-02-13

Abstract excerpt

<h4>Background: </h4> Hepatitis B virus (HBV) infection is one of the major causes of chronic liver disease which progresses from hepatitis to liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). Early detection and laboratory based screening test of HCC is still a major challenge. HBV induces hepatocarcinogenesis through viral genome integration, chromosomal aberrations and modulation of host signaling p...

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Literature Corpus work: a238768f-2d8f-56da-84de-389637bc13c2
DOI: 10.22541/au.167629507.76296960/v1

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