Influence of polymorphisms in the Wnt/β-catenin pathway genes on hepatocellular carcinoma risk in a Chinese Han population.

doi:10.1097/MD.0000000000006127

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Article

Influence of polymorphisms in the Wnt/β-catenin pathway genes on hepatocellular carcinoma risk in a Chinese Han population.

Medicine - 1 Mar 2017

Li Qing-Min, Zhang Feng-Qin, Li Ya-Feng, Xian Qing-Jie, Zhang Yan-Qiang, Li Peng

Abstract excerpt

The Wnt/β-catenin pathway plays a vital role in initiating and sustaining hepatocellular carcinoma (HCC). However, few studies have investigated polymorphisms in the Wnt/β-catenin signaling pathway genes in the Chinese Han population. The aim of the present retrospective study was to investigate the correlations between polymorphisms of the Wnt/β-catenin signaling pathway genes (CTNNB1 and WNT2) and HCC...

Topics

Adult
Aged
Alleles
Asian People
Carcinoma, Hepatocellular
Case-Control Studies
Disease Progression
Female
Genotype
Hepatitis B, Chronic
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Cirrhosis

Liver Neoplasms

Male

Middle Aged

Neoplasm Staging

Odds Ratio

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 28328801
DOI: 10.1097/MD.0000000000006127
PMCID: PMC5371438

Genes

CTNNB1
WNT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-28328801-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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