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Article

The genomic landscape of Mongolian hepatocellular carcinoma.

Nature communications - 1 Sept 2020

Candia Julián, Bayarsaikhan Enkhjargal, Tandon Mayank, Budhu Anuradha, Forgues Marshonna, Tovuu Lkhagva-Ochir, Tudev Undarmaa, Lack Justin, Chao Ann, Chinburen Jigjidsuren, Wang Xin Wei

Abstract excerpt

Mongolia has the highest incidence of hepatocellular carcinoma (HCC) in the world, but its causative factors and underlying tumor biology remain unknown. Here, we describe molecular characteristics of HCC from 76 Mongolian patients by whole-exome and transcriptome sequencing. We present a comprehensive analysis of mutational signatures, driver genes, and molecular subtypes of Mongolian HCC compared to 373 HCC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32873799
DOI: 10.1038/s41467-020-18186-1
PMCID: PMC7462863

Genes

CTNNB1
PNRC2
SPTA1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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