Article
C57BL/6-derived mice and the Cdh23ahl allele - Background matters.
Hearing research - 1 Jun 2025
Newton Sherylanne, Aguilar Carlos, Bowl Michael R
Abstract excerpt
C57BL/6-derived mice are the most utilised mice in biomedical research, and yet actually there is no such thing as a generic C57BL/6 mouse. Instead, there are more than 150 C57BL/6-derived sub-strains recognised by the Mouse Genome Informatics (MGI) database, each of which carry sub-strain-specific fixed genetic differences that can potentially lead to phenotypic differences affecting a single, or multiple...
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