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Article

miR-27b-3p modulates liver sinusoidal endothelium dedifferentiation in chronic liver disease

30 Apr 2025

Abstract excerpt

BACKGROUND: During chronic liver diseases, LSECs undergo a dedifferentiation process contributing to the development of hepatic microvascular dysfunction. Although microRNAs (miRNAs) have been associated with chronic liver disease, their role as modulators of liver endothelial phenotype is mostly unknown. Therefore, the aim of this study was to analyze miRNAs as regulators of hepatic sinusoidal endothelial...

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PMID: 40304581
DOI: 10.1097/hc9.0000000000000700

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