Transition from hepatic steatosis to steatohepatitis: Unique microRNA patterns and potential downstream functions and pathways

Abstract excerpt

BACKGROUND AND AIM: This study aimed to explore the unique miRNA responsible for transition from hepatic steatosis to steatohepatitis and to investigate the functions and pathways of their downstream targets. METHODS: Microarray and stem-loop reverse transcription-polymerase chain reaction were utilized to detect dysregulated miRNA in a rat model. SAM, PAM and clustering analysis were jointly applied to calculate...

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