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Integrated population clustering and genomic epidemiology with PopPIPE

28 Apr 2025

Abstract excerpt

Genetic distances between bacterial DNA sequences can be used to cluster populations into closely related subpopulations and as an additional source of information when detecting possible transmission events. Due to their variable gene content and order, reference-free methods offer more sensitive detection of genetic differences, especially among closely related samples found in outbreaks. However, across longer...

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PMID: 40294103
DOI: 10.1099/mgen.0.001404

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