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Exploring the Role of Mitochondrial Sirtuin 3 Gene in Gastric Cancer Risk Based on SNP Analysis and LORD-Q Assay.

Biochemical genetics - 1 Apr 2026

Mahjabeen Ishrat, Hussain Muhammad Zahid, Haq Maria Fazal-Ul, Mehmood Azhar, Haris Muhammad Shahbaz, Khan Shereen Ali, Chaudhry Anum, Hakim Farzana, Abbasi Ayesha Zulfiqar, Kayani Mahmood Akhtar

Abstract excerpt

Mitochondrial sirtuin 3 (SIRT3) is a gene involved in key functions like acetylation, DNA repair, stress response, and tumorigenesis. Several studies have been published that showed the role of SIRT3 in various cancers. Still, few studies have been reported on the genetic and expression variation of the SIRT3 gene in gastric carcinogenesis. This study was designed to explore the involvement of the SIRT3 gene in...

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PMID: 40293630
DOI: 10.1007/s10528-025-11119-x

Genes

SIRT3
GC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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