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Article

Mitochondrial sirtuins genetic variations and gastric cancer risk: Evidence from retrospective observational study.

Gene - 10 Jan 2022

Mahjabeen Ishrat, Rizwan Muhammad, Fareen Gul, Waqar Ahmed Malik, Farooq Khan Amir, Akhtar Kayani Mahmood

Abstract excerpt

AIMS: The purpose of the present study was to analyze the role of selected polymorphisms of SIRT3 and SIRT5 in gastric carcinogenesis. METHODS: For this study, 500 blood samples of GC patients and 500 blood samples of healthy individuals were collected. Six selected polymorphisms of mitochondrial sirtuins were analyzed for analysis using Tetra-Arms PCR followed by DNA sequencing. RESULTS: Mutant allele...

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PMID: 34500051
DOI: 10.1016/j.gene.2021.145951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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