Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new protein isoform encoded by human circular RNA circSLC8a1 contributes to cardiac remodelling.

Cardiovascular research - 12 Jun 2025

Li Feiya, Du William Weidong, Li Xiangmin, Wen Shuoyang, Xu Jindong, Yang Qiwei, Zhang Chao, Ye Ting, Wei Jinfeng, Wang Sheng, Wu Nan, Qadir Javeria, Yang Burton Baihua

Abstract excerpt

AIMS: Circular RNA circSLC8a1 has been previously suggested to possess translation potential, but experimental evidence supporting this notion has been lacking. We aim to understand the functions of circSLC8a1 and its translated protein in cardiac remodelling. METHODS AND RESULTS: To elucidate the functional significance of circSLC8a1, we established a transgenic mouse line expressing circSLC8a1 and its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Heart Failure
Share to Mitochondria, Heart

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myocytes, Cardiac

Share to Protein Biosynthesis

Share to Protein Isoforms

Share to RNA, Circular

Share to Ventricular Function, Left

Share to Ventricular Remodeling

Source

Open in PubMed Open full text

Identifiers

PMID: 40273295
DOI: 10.1093/cvr/cvaf058
PMCID: PMC12160813

Genes

POLRMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new protein isoform encoded by human circular RNA circSLC8a1 contributes to cardiac remodelling.PMID 40273295Read ↗

Circular RNA circFTO promotes pressure overload-induced cardiac hypertrophy via encoding a novel protein FTO-36aaSemantic proximity Read ↗

Genomic analysis of circular RNAs in heartSemantic proximity Read ↗

A landscape of circular RNA expression in the human heart.Semantic proximity Read ↗

Circular RNA Expression for Dilated Cardiomyopathy in Hearts and Pluripotent Stem Cell–Derived CardiomyocytesSemantic proximity Read ↗

K9HeartCircDB: A circRNA Atlas of Tachypacing-Induced Canine Dilated CardiomyopathySemantic proximity Read ↗

MicroRNA-574 Regulates FAM210A Expression and Influences Pathological Cardiac RemodelingSemantic proximity Read ↗

Translation of Circular RNAsSemantic proximity Read ↗

Circular PVT1 promotes cardiac fibroblast activation via sponging miR-30a-5p and miR-125b-5pSemantic proximity Read ↗

3’ to 5’ Translation of Circular RNAs?Semantic proximity Read ↗

Global Profile of tRNA-Derived Small RNAs in Pathological Cardiac Hypertrophy Plasma and Identification of tRF-21-NB8PLML3E as a New Hypertrophy MarkerSemantic proximity Read ↗

RBM20 Regulates Circular RNA Production From the Titin GeneSemantic proximity Read ↗

Translational Control in Cardiac Pathophysiology and Therapeutic Development: When mRNA Meets the HeartSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.