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Identification and exploration of key genes associated with radioresistance in lung adenocarcinoma

19 Apr 2025

Abstract excerpt

BACKGROUND: Radiation resistance in lung adenocarcinoma (LUAD) remains a primary obstacle limiting radiotherapy efficacy. However, the detailed factors and molecular mechanisms influencing LUAD radiosensitivity are not fully understood. METHODS: Radioresistance-related genes (RRRGs) were screened by RNA sequencing and bioinformatics analysis, and a prediction model for radiotherapy efficacy was developed via...

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PMID: 40253319
DOI: 10.1186/s12935-025-03783-1

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