Long-term culture of chicken tracheal organoids for the purpose of avian influenza virus research

Abstract excerpt

There is an increasing need for reproducible long-term in vitro primary cell culture systems that are representative of the avian respiratory tract to study pathogens like highly pathogenic avian influenza viruses (HPAIVs), which threaten poultry, wildlife, and human health. Self-renewing organoid cultures allow for long-term culture, due to the presence of tissue-resident stem cells, and can approximate the in...

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