Back to search

Article

Human nasal epithelial cell organoids as a platform for subsequent passage stability, ALI culture differentiation and influenza virus infection modeling

2026-04-16

Abstract excerpt

<title>Abstract</title> <p>The cultures of human nasal epithelial cells (NECs) are good surrogate models for studying immune responses. Three-dimensional (3D) organoids have emerged as an alternative for nasal epithelium, serving as robust platforms for modeling respiratory viral infections. We aimed to generate human NEC organoids and to determine their cellular characteristics as an in vitro model for air-liqui...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ce368901-43f5-5dbc-9ee4-fe7becee5d2a
DOI
10.21203/rs.3.rs-9241349/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Human nasal epithelial cell organoids as a platform for subsequent passage stability, ALI culture differentiation and influenza virus infection modelingDOI 10.21203/rs.3.rs-9241349/v1
Human nasal organoids sustain reproducible airway epithelial differentiation and influenza virus-host innate immune interactionSemantic proximity
Human Nasal Organoids Model SARS-CoV-2 Upper Respiratory Infection and Recapitulate the Differential Infectivity of Emerging VariantsSemantic proximity
Human airway organoids as a versatile model to study BSL-4 virus replication and pathogenesisSemantic proximity
Characterization of human nasal organoids from chronic rhinosinusitis patientsSemantic proximity
Transcriptomic Analysis of Air–Liquid Interface Culture in Human Lung Organoids Reveals Regulators of Epithelial DifferentiationSemantic proximity
A comparative study of in vitro air–liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolutionSemantic proximity
From Submerged Cultures to 3D Cell Culture Models: Evolution of Nasal Epithelial Cells in Asthma Research and Virus InfectionSemantic proximity
The human nose organoid respiratory virus model: an ex-vivo human challenge model to study RSV and SARS-CoV-2 pathogenesis and evaluate therapeuticsSemantic proximity
Cell culture differentiation and proliferation conditions influence the <i>in vitro</i> regeneration of the human airway epitheliumSemantic proximity
Impact of cell culture model systems on SARS-CoV-2 and MERS-CoV infection dynamics and antiviral responsesSemantic proximity
Influenza Virus Infection of an Immunocompetent Organotypic Model of the Human Respiratory MucosaSemantic proximity
Cell Culture Differentiation and Proliferation Conditions Influence the In Vitro Regeneration of the Human Airway EpitheliumSemantic proximity
Select a neighboring publication to make it the new centre.