Spatial structure facilitates evolutionary rescue by drug resistance.

Abstract excerpt

Bacterial populations often have complex spatial structures, which can impact their evolution. Here, we study how spatial structure affects the evolution of antibiotic resistance in a bacterial population. We consider a minimal model of spatially structured populations where all demes (i.e., subpopulations) are identical and connected to each other by identical migration rates. We show that spatial structure can...

Topics

• Mutation
• Anti-Bacterial Agents
• Drug Resistance, Bacterial
• Bacteria
• Biological Evolution
• Computational Biology